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How spatial proteomics research is helping scientists find Alzheimer's disease earlier


DESPITE decades of research, many fundamental questions about Alzheimer’s disease remain unanswered, including how the disease begins and progresses across different regions of the brain. Researchers are working to uncover those answers by looking more closely at the proteins involved in disease progression, where they are located and how they change over time.

 

In this video, Dr. Jun Qu, Ph.D., professor, Department of Pharmaceutical Sciences, University at Buffalo, explains how advances in spatial proteomics and mass spectrometry are helping researchers map proteins with greater precision and identify early signals associated with Alzheimer’s disease.

 

By discovering new potential biomarkers and therapeutic targets, this research could help enable earlier detection, more effective treatments and a more precise approach to understanding and managing the disease.



Watch other videos in this series


We’re in a Proteomics Revolution

Advances across the scientific workflow are enabling researchers to analyze thousands of proteins across increasingly large numbers of samples with speed and reliability that would have been difficult to imagine just a few years ago.

Every heart tells a different story

Hear disease remains the world’s leading cause of death, yet the biology behind it can vary significantly from one person to another, particularly and between women and men.

When cancer comes back


Discover how proteomics and mass spectrometry are advancing precision oncology, helping researchers better understand recurrent cancers and personalize treatment decisions.