clear search
Search
Search Suggestions
Recent searches Clear History
Talk with Us
Allergen Encyclopedia
Table of Contents

Whole Allergen

e70 Goose feathers

e70 Goose feathers Scientific Information

Type:

Whole Allergen

Display Name:

Goose feathers

Family:

Anatidae

Latin Name:

Anser anser

Other Names:

Goose, Toulouse Goose, Grey Goose, Greylag

Environmental Characteristics

Other topics

The genera Anser and Branta should both be considered. Anser includes many wild Geese with well-known domestic relatives. This group includes Anser anser (European) and species of Africa and Asia. Branta includes wild Geese like the Canada Goose (Branta Canadensis) and the Brants (most notably Branta bernicla). 

Route of Exposure

Other topics

Goose down is widely used for stuffing pillows, duvets and jackets.

Clinical Relevance

IgE mediated reactions
Asthma, allergic rhinitis and allergic conjunctivitis may result following exposure to Duck feathers, epithelial cells or droppings. The allergic manifestations may present as Extrinsic Allergic Alveolitis (1).

Of 269 adult patients with suspected skin and respiratory allergies tested for feathers with skin specific IgE tests, 9% of the whole group and 14% of those positive to inhalant allergens were positive to any feather allergen. Two reacted to duck feathers, 12 to goose and 15 to chicken feathers. Symptoms were reported by 58% of feather skin specific IgE positive patients and 55% by other skin specific IgE positive patients. Positive RAST specific IgE tests were surprisingly few which may be explained by possible contamination of the skin extracts by mite allergens (2).

Extrinsic Allergic Alveolitis, also known as Hypersensitivity pneumonitis, 'Bird Fancier's Lung' and 'Farmer's Lung', is a disease of inflammation of the lung parenchyma in the terminal bronchioles and alveoli. Symptoms may start soon after exposure to bird allergens or after many years, and may include breathlessness, cough, occasional chills, and fever. Death may also result.

The allergenic proteins may be found in bird serum, droppings, and feathers. Contact may result from handling birds, cleaning their cages, or exposure to the organic dust drifting from where the birds reside.

Exposure to avian antigens results in the development of immunoglobulins including IgE (3), IgM (4), IgA and various IgG subclasses (5-7). The development of specific IgG and IgA antibodies to avian proteins does not necessarily indicate disease (8).

Diagnosis is based on a characteristic clinical picture and a typical x-ray pattern, accompanied by the presence of specific IgG antibodies (9).

Clinical allergy to commercial feather products is less common than usually thought, as a result of the removal of rough dry dust, washing and drying at 125OC. The allergens derived from unrefined feathers include bird serum proteins, bird droppings, and feather mites (2)

Polyester-filled pillows contain significantly more total weight of Der p 1 mite allergen (Dermatophagoides pteronyssinus) than feather-filled pillows (10).

Molecular Aspects

Cross-reactivity

Cross-reactivity between Goose and other phylogenetically related bird species may be expected, and in Chicken-allergic patients, significant IgE titers to Parrot, Budgerigar, Chicken, Pigeon, Goose and Duck have been reported (11, 12).

Last reviewed December 2024

References
  1. Plessner M. [A disease of feather sorters: duck fever]. Archives des maladies professionnelles de medecine du travail et de securite sociale. 1960;21:67-9.
  2. Kilpiö K, Mäkinen-Kiljunen S, Haahtela T, Hannuksela M. Allergy to feathers. Allergy. 1998;53(2):159-64.
  3. Tauer-Reich I, Fruhmann G, Czuppon AB, Baur X. Allergens causing bird fancier's asthma. Allergy. 1994;49(6):448-53.
  4. Martínez-Cordero E, Aguilar León DE, Retana VN. IgM antiavian antibodies in sera from patients with pigeon breeder's disease. Journal of clinical laboratory analysis. 2000;14(5):201-7.
  5. Baldwin CI, Todd A, Bourke SJ, Allen A, Calvert JE. IgG subclass responses to pigeon intestinal mucin are related to development of pigeon fanciers' lung. Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology. 1998;28(3):349-57.
  6. Todd A, Coan R, Allen A. Pigeon breeders' lung; IgG subclasses to pigeon intestinal mucin and IgA antigens. Clinical and experimental immunology. 1993;92(3):494-9.
  7. Yoshizawa Y, Miyashita Y, Inoue T, Sumi Y, Miyazaki Y, Sato T, et al. Sequential evaluation of clinical and immunological findings in hypersensitivity pneumonitis: serial subclass distribution of antibodies. Clinical immunology and immunopathology. 1994;73(3):330-7.
  8. Andersen P, Schønheyder H. Antibodies to hen and duck antigens in poultry workers. Clinical allergy. 1984;14(5):421-8.
  9. Rodríguez de Castro F, Carrillo T, Castillo R, Blanco C, Díaz F, Cuevas M. Relationships between characteristics of exposure to pigeon antigens. Clinical manifestations and humoral immune response. Chest. 1993;103(4):1059-63.
  10. Kemp TJ, Siebers RW, Fishwick D, O'Grady GB, Fitzharris P, Crane J. House dust mite allergen in pillows. BMJ (Clinical research ed). 1996;313(7062):916.
  11. de Maat-Bleeker F, van Dijk AG, Berrens L. Allergy to egg yolk possibly induced by sensitization to bird serum antigens. Annals of allergy. 1985;54(3):245-8.
  12. van Toorenenbergen AW, Huijskes-Heins MI, Gerth van Wijk R. Different pattern of IgE binding to chicken egg yolk between patients with inhalant allergy to birds and food-allergic children. International archives of allergy and immunology. 1994;104(2):199-203