Episode 033
Dust mites to dinner plates: Unexpected insect allergies in clinical practice
Episode summary
Did you know the average person unknowingly consumes about 2 pounds of insects or insect parts annually? This startling fact underscores the ubiquitous presence of insects in our environment and diet, presenting unique challenges in allergy diagnosis and patient management. This episode of ImmunoCAST explores the multifaceted world of insect-related allergies, moving beyond common respiratory or stinging triggers to uncover lesser-known presentations. We explore the "Pancake Syndrome" and its link to dust mites, discuss the cross-reactivity between dust mites and shellfish, and examine the allergenic potential of insect-derived food additives. By understanding these complex interactions, clinicians can enhance their diagnostic acumen and provide more comprehensive care for patients with suspected insect allergies.
Episode resources
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- Sustainable, edible and nutritious – think about insects again!. HEALTH AND FOOD SAFETY - Sustainable, edible and nutritious – think about insects again! (n.d.). https://ec.europa.eu/newsroom/sante/items/787829/en
- Entomophagy (eating insects). Center for Invasive Species Research. (2022, September 28). https://cisr.ucr.edu/entomophagy-eating-insects
- U.S. Food and Drug Administration. "Food Defect Levels Handbook." Food and Drug Administration, https://www.fda.gov/food/current-good-manufacturing-practices-cgmps-food-and-dietary-supplements/food-defect-levels-handbook. Accessed April 2025
- De Marchi L, Wangorsch A, Zoccatelli G. Allergens from Edible Insects: Cross-reactivity and Effects of Processing. Curr Allergy Asthma Rep. 2021 May 30;21(5):35.
- Sánchez-Borges M, Suárez-Chacon R, Capriles-Hulett A, Caballero-Fonseca F, Iraola V, Fernández-Caldas E. Pancake syndrome (oral mite anaphylaxis). World Allergy Organ J. 2009 May;2(5):91-6.
- Sandip D. Kamath, Tropomyosin: A cross-reactive invertebrate allergen, Editor(s): Scott H. Sicherer, Encyclopedia of Food Allergy (First Edition), Elsevier, 2024, Pages 310-319, ISBN 9780323960199,
- Rohrig, B. (n.d.). Eating with your eyes: The Chemistry of Food Colorings. American Chemical Society. https://www.acs.org/education/chemmatters/past-issues/2015-2016/october-2015/food-colorings.html
