The ImmunoCAP ISAC solid-phase allergen chip assay is an in vitro diagnostic test that allows for simultaneous measurement of specific IgE antibodies to 112 allergen components from 51 sources. This innovative assay allows your team to provide clinicians with a significant amount of allergen specific IgE antibody information in a single step, from a single sample. The assay is clinically documented in more than 220 peer reviewed articles, including a global validation study.1 The ImmunoCAP ISAC test is the result of a combination of innovative biochip technology and cutting-edge research in molecular allergology.
Based on modern biochip technology, ImmunoCAP ISAC assay is an immunoassay platform in which allergen components are immobilized in a microarray. This test is a two-step assay that can be completed in less than 4 hours:
IgE antibodies from the patient sample bind to the immobilized allergen components
Allergen-bound IgE antibodies are detected by a fluorescence labeled anti-IgE antibody
Patelis, A. et al. Multiplex component-based allergen microarray in recent clinical studies. Clinical & Experimental Allergy. 2016;46:1022–1032.