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ImmunoCAP Phadiatop and ImmunoCAP Phadiatop Infant

Differentiating between atopic and nonatopic patients

ImmunoCAPTM PhadiatopTM and ImmunoCAP Phadiatop Infant blood tests are initial, qualitative screenings tests. ImmunoCAP Phadiatop and ImmunoCAP Phadiatop Infant measure IgE antibodies to a well-balanced mixture of relevant allergens, which are often implicated in causing allergic diseases in adults and in young children, respectively.

Offering ImmunoCAP Phadiatop and ImmunoCAP Phadiatop Infant can add value to your laboratory. 

These tests help clinicians:1-7

  • Identify patients with a high likelihood of allergic disease (that is, atopic individuals)
  • Differentiate IgE-mediated atopic allergy from other allergy-like symptoms
  • Identify patients who need further specific IgE testing




ImmunoCAP Phadiatop indicates atopy 8-12

ImmunoCAP Phadiatop are assays for the graded determination of atopy with semi quantitative or qualitative results. With these tests, the higher the IgE antibody level (i.e., degree of atopy), the higher the risk for symptomatic allergy.8-12

References
  1. Eriksson NE. Allergy screening with Phadiatop and CAP Phadiatop in combination with a questionnaire in adults with asthma and rhinitis. Allergy. 1990;45(4):285-292.
  2. Wever-Hess J, Kouwenberg JM, Duiverman EJ, et al. Prognostic characteristics of asthma diagnosis in early childhood in clinical practice. Acta Paediatrica. 1999; 88(8): 827-834.
  3. Halvorsen R, Jenner A, Hagelin EM, et al. Phadiatop Infant in the Diagnosis of Atopy in Children with Allergy-Like Symptoms. Int J Pediatr. 2009; 460737.
  4. Ballardini N, Nilsson c, Nilsson M, et al. ImmunoCAP Phadiatop Infant--a new blood test for detecting IgE sensitisation in children at 2 years of age. Allergy. 2006;61(3):337-343.
  5. Williams PB, Siegel C, Portnoy J. Efficacy of a single diagnostic test for sensitization to common inhalant allergens. Ann Allergy Asthma Immunol. 2001;86(2):196-202.
  6. Nilsson C, Lilja G, Nordlund M, et al. Phadiatop Infant(®) detects IgE-mediated diseases among pre-school children: a prospective study. Pediatr Allergy Immunol. 2012;23(2):159-165.
  7. Lau S, Nilsson M, Sulser C, et al. Use of Phadiatop Infant in diagnosis of specific sensitization in young children with wheeze or eczema. Pediatr Allergy Immunol. 2008;19(4):337- 41.
  8. Nilsson M., Rudengren M., Söderström L., Ytterström U. (2004, June) Quantitative measurement of Phadiatop®. EAACI, Amsterdam.
  9. Paganelli R, et al. Specific IgE antibodies in the diagnosis of atopic disease. Clinical evaluation of a new in vitro test system, UniCAP, in six European allergy clinics. Allergy. 1998; 3(8): 63-8.
  10. Wever A M J et al. Evaluation of the Phadiatop® test in an epidemiological study. Allergy 1990;45: 92-97
  11. Matricardi P M et al. Evaluation of the overall degree of sensitization to airborne allergens by a single serologic test: Implications for epidemiologic studies of allergy J Allergy Clin Immunol 1994;93: 68-79
  12. Bruno, G, Cantani, A, Ragno, V, Milita, O, Zirulo, G, Businco, L. Natural history of IgE antibodies in children at risk for atopy. Ann Allergy. 1995;74:431-436.